ncRNA name | CTGF siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, RT-PCR, Western blot, immunohistochemistry, TUNEL assay |
Expression pattern | associated |
Functional description | SiRNA-mediated inhibition of CTGF mRNA inhibited retinal VEGF and TGF-β(2) and also resulted in a significant decrease in apoptosis. |
PubMed ID | 20039857 |
Year | 2010 |
Title | The role of CTGF in the diabetic rat retina and its relationship with VEGF and TGF-β(2) , elucidated by treatment with CTGFsiRNA. |
Drug-related ncRNA | NO |
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